Research Animal Resources Letter to University of Wisconsin ACUC - July 10, 2003

The University of Wisconsin Madison

To: Tim Mulcahy
Chair, All Campus ACUC

From: [REDACTED]
RARC

RE: Dr. Terasawa and Protocol G00146

Date: July 10, 2003

Enclosed please find my report of the review of the clinic histories of Dr. [REDACTED] animals on protocol G146 for the last three years. Also enclosed is a memo from Dr. [REDACTED] reporting the results of her own investigation of laboratory notebooks and clinical records.

As you can see, there have been a variety of deviations from her approved protocols over this period of time. There have also been more negative outcomes than expected for the animals on the push pull perfusion studies, especially for aged animals. I understand that the All Campus ACUC will decide whether she can continue to do animal research here at the university, and may allow the Graduate School ACUC to lift her suspension and approve her most recent protocol at their discretion. If this is the case, I submit the following ideas to prevent future reoccurrences of these types of problems.

First, the [REDACTED] veterinary staff should review the clinical records of all of her current animals on a regular basis and report to the Graduate School ACUC any events of concern (once a month or once every two months.) Second, someone should review her current laboratory notebooks and report to the ACUC as above (perhaps [REDACTED] from the [REDACTED]. Third, a letter should be crafted to Dr. [REDACTED] explaining to her that further serious violations will result in loss of ability to perform animal research at the university. Last, Dr. [REDACTED] should reply in writing that she understands and accepts these conditions.

I believe a period of one year of close observation should be sufficient to assure compliance and understanding by Dr. [REDACTED] and her staff.

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